Preprint for Prosculpt is online
Have you ever wanted to get into de novo protein design, but didn’t know where to start? Or are you just tired of writing messy one-off scripts to glue together RFdiffusion, ProteinMPNN, and structure prediction tools (ColabFold, AF3, Boltz2)? Then we have a treat for you!
We have released Prosculpt: an easy-to-use, end-to-end computational workflow for de novo protein design. Go from a single YAML configuration file to a ranked set of designed structures and metrics, ready for manual inspection and ordering.